Review
Aug 2026
cGAS–STING signaling in aging and age-related diseases: therapeutic promise and precaution
Evidence linking dysregulated cGAS–STING activation to inflammatory remodeling, senescence-associated changes, cell injury, fibrosis, and tissue dysfunction is synthesized, while highlighting the context-dependent roles of this pathway across physiological aging and ARDs.
Yingying Xu, Weidong Wu, Yifan Guo et al.
· Archives of pharmacal resear... · 0 citations