Author

Jing-Ping Yun

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Open access Aug 2026

Transcriptomic profiling of lineage transformation and actionable therapy opportunities in EGFR-mutant non-small cell lung cancer evolving to small cell lung cancer

The immune landscape of T-SCLC is more immunosuppressed than EGFRm LUAD, yet more immunologically active than that of P-SCLC, and this immune profile provides a rationale for integrating immunotherapy with chemotherapy in T-SCLC.

Hui Yu, Meichen Li, Xiao-Die Li et al. · Journal of Translational Med... · 0 citations

Open access Aug 2026

p38β-mediated BiP phosphorylation drives stemness and chemoresistance by suppressing UPR activation in hepatocellular carcinoma

It is discovered that p38β/MAPK11 phosphorylation of BiP promotes stemness and chemoresistance in HCC, revealing a targetable p38β–BiP axis in HCC.

Liang Xu, I. B. Huang, Minghe Zhang et al. · Nature Communications · 0 citations