Content of image described in text. Abstract Background Bipolar disorder (BD) is characterized by mood fluctuations and is prone to misdiagnosis as major depressive disorder (MDD). Quantifying the relationship between symptom fluctuations and conversion risk is essential for early identification. Methods In a national...
To examine whether pretreatment resting-state functional connectivity (rsFC) of hippocampal subregions is associated with 12-week escitalopram treatment outcomes in major depressive disorder (MDD).
A total of 87 patients with MDD received 12 weeks of escitalopram monotherapy and underwent resting-state funct...
Feng-Xia Zhang, Xiao-Ya Li, Ling Zhang et al.· Frontiers in Psychiatry· 0 citations
Abstract Background Selective serotonin reuptake inhibitors (SSRIs) represent an effective treatment for major depressive disorder (MDD). This study employed glutamate chemical exchange saturation transfer (GluCEST) magnetic resonance imaging (MRI) to compare glutamate-sensitive signals in the prefrontal cortex and hip...
Xi-Man Hou, Hao-Nan Wang, Rui Liu et al.· Psychological Medicine· 0 citations
A multi-level perspective on the dynamic neural mechanisms of suicidality is provided and regional and network-level dynamic abnormalities may differentially contribute to trait SI, recent SI, and treatment-related improvements.
Yi-Fan Jing, Lin Jing, Xiong-Ying Chen et al.· Journal of Affective Disorde...· 0 citations
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