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Author

Jing-Jing Xie

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2 papers indexed here

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Oct 2026

CYP2U1: a cardiac metabolic switch alleviating obesity cardiomyopathy via lipid metabolic reprogramming.

Cardiac-specific overexpression of CYP2U1 safeguards against high-fat diet (HFD)-induced myocardial dysfunction and limits obesity-driven cardiac inflammation by coupling suppression of the NF-κB/C/EBPβ-IL-6 axis with a shift in lipid mediators toward DHA-derived specialized pro-resolving mediators.

Jing Chen, Zhong-Xi Chen, Yu-Bin Lan et al. · 0 citations
Open access Sep 2026

Spermidine ameliorates homosalate-induced mouse oocyte defects via regulation of mitochondria and cytoskeleton.

Homosalate (HMS) is an organic ultraviolet filter widely used in personal care products. Although its endocrine-disrupting properties are recognized, its impact on oocytes remains poorly characterized. Through network pharmacology, Smart-seq2 sequencing, and in vitro models, our findings indicate that HMS exposure dela...

Fei Meng, Yuan Yao, Zheng-Ke Gao et al. · 0 citations

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