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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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Jing-Jing Liu

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Review Open access Oct 2026

Dynamic remodeling of microglial responses in Alzheimer’s disease: heterogeneous states, spatiotemporal progression, and immunometabolic dysregulation

Alzheimer’s disease (AD) is characterized by progressive neuroinflammation involving microglia whose functional responses extend far beyond the classical M1/M2 framework and form a dynamically heterogeneous continuum. Here, we review recurrent disease-associated microglia (DAM) states and transcriptional programs, incl...

Si-Min Han, Shan-Shan Wang, Jing-Jing Liu et al. · 0 citations
Review Sep 2026

From physiological homeostasis to pathological injury: Cell-specific functions, imbalance mechanisms, and disease biomarker value of brain lipid droplets.

Lipid droplets (LDs) are versatile cellular structures that consist of a core made of neutral lipids, surrounded by a monolayer of phospholipid membrane. Beyond energy storage, LDs serve as critical immunometabolic platforms that govern microglial activation states and neuroinflammatory cascades. Their formation and fu...

Qing Zhang, Xiao-Li Liu, Le Shi et al. · 0 citations

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