Author

Jing-Jing Cai

h-index 6 View on Semantic Scholar

We have 3 of 12 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Sep 2026

Novel mTORC1 Booster LAPTM4A Potentiates Pathological Cardiac Hypertrophy.

BACKGROUND Excessive unnecessary protein accumulation in cardiomyocyte is a leading contributor for pathological cardiac hypertrophy and has been found closely regulated by the mTORC1 (mechanistic target of rapamycin complex 1) signaling and lysosome transmembrane proteins. However, the precise regulatory mechanism str...

Yu-Feng Hu, Wei Li, Man-Li Hu et al. · Circulation · 0 citations

Aug 2026

Facilitation of Autophagosome-Lysosome Fusion by LAPTM4A: A Novel Strategy for Attenuating Myocardial Ischemia-Reperfusion Injury.

BACKGROUND Myocardial ischemia-reperfusion (MIR) injury compromises therapeutic effects of revascularization and leads to functional impairment and exacerbation of structural damage in the heart. Limiting the damage caused by MIR is crucial but is still an unmet clinical need because of the complexity of the underlying...

Si-Yi Zhou, Jia-Yi Liu, Man-Li Hu et al. · Circulation · 0 citations

Open access Aug 2026

COL1A1-Enhanced CD44/SLC7A11 Interaction and Cystine Uptake Result in CD34+ Foam-Like Macrophage Accumulation in Transplant Arteriosclerosis.

BACKGROUND Chronic transplant arteriosclerosis is the primary cause of long-term graft failure. Selectively targeting specific inflammatory macrophage subpopulations is essential for inhibiting the primary triggers of inflammatory and immune responses. Therefore, elucidating the origins and regulatory mechanisms of the...

Junru Wu, Tian He, Mengyao Qi et al. · Circulation · 0 citations