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Author

Jing-Hui Du

2 papers indexed here

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Open access Aug 2026

Uhrf1‐Mediated PKM2 Degradation via Ubiquitination Alleviates Inflammation and Pyroptosis in Inflammatory Bowel Disease

This work uncovered Uhrf1‐dependent PKM2 ubiquitination/degradation as a previously unrecognized therapeutic axis for IBD, while positioning EPT as a molecular glue capable of targeting the Uhrf1–PKM2 complex.

Juan Zhang, Xin-rong Xu, Hui-lin Zhang et al. · 0 citations
Review Open access Aug 2026

Gut dysbiosis, metabolic signals, and pulmonary immune reprogramming: decoding the gut microbiota -immune axis in stroke-associated pneumonia

Stroke-associated pneumonia (SAP) is the most common infectious complication following acute stroke. The limited efficacy of conventional antimicrobial therapy suggests that SAP may be fundamentally a syndrome driven by dysregulated cross-system interactions. This review proposes the “gut microbiota–immune axis” (GMIA)...

Li Yang, Jing Han, Shengqiang Li et al. · 0 citations

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