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Review Open access Sep 2026

From mutation detection to treatment decisions: CRISPR-enabled diagnostics for drug-resistant tuberculosis

Effective management of drug-resistant tuberculosis requires molecular assays that not only detect Mycobacterium tuberculosis but also identify resistance-associated variants, support drug-level interpretation, and indicate when broader confirmatory testing is needed. This narrative review applies a mutation-to-drug-to...

Wei-Jia Yi, Fu-Kang Luo, Dian-Ping Yi et al. · 0 citations
Open access Sep 2026

AI-Predicted Full-Spectrum UV Correction Factors: An Analyte-Standard-Free Framework for Reaction Yield Quantification

High-throughput experimentation (HTE) accelerates molecular discovery but struggles to quantify yields without pure analyte standards. The current need to purify standards increases cost, complexity, and cycle time, limiting the scalability of new molecular discovery. Here, we introduce an integrated “detect-predict”...

Jiu-Chuang Yuan, Ming-Jun Yang, Fan Yan et al. · 0 citations

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