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Author

Jing Dong

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2 papers indexed here

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Open access Oct 2026

Germline DDX41 defines a distinct subgroup in MDS undergoing transplantation with reduced relapse and improved survival.

Germline DDX41 variants are a recognized cause of adult myelodysplastic neoplasms (MDS), characterized by distinct biological features and favorable prognosis. The independent effect of DDX41 status on outcomes after allogeneic transplantation, the role of conditioning intensity, and treatment-related toxicity risk rem...

N. Gagelmann, Christopher R. Reilly, Archana Sasi et al. · 0 citations
Open access Sep 2026

Mitochondrial Genomic Alterations in Pediatric Acute Lymphoblastic Leukemia: Implications for Methotrexate‐Induced Neurotoxicity and Ethnic Disparities

Methotrexate (MTX)‐induced neurotoxicity is a serious complication in pediatric acute lymphoblastic leukemia (ALL), with observed ethnic disparities in risk. To investigate the role of mitochondrial DNA (mtDNA) variation, we performed whole mtDNA sequencing in 94 children with ALL, including 62 Hispanic patients. We id...

Jing Han, Shahram Arsang-Jang, Paul L. Auer et al. · 0 citations

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