4 papers indexed here
We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.
Not the right person? Other researchers publish under this name.
With the rapid expansion of high-speed railway (HSR) infrastructure, ensuring the long-term stability of geosynthetic-reinforced soil (GRS) walls under repeated traffic loading is critical. This study investigates the dynamic mechanical behaviour of HSR GRS walls using a combination of physical model tests and three-dimensional dynamic numerical simulations. A moving vehicle loading device developed by the authors was employed to realistically simulate the driving effects of high-speed trains, addressing the limitations of traditional sinusoidal loading systems. Results indicate that wall crest settlement increases rapidly during the initial 500 cycles (contributing ∼50% of total settlement) before exhibiting a continued, albeit reduced, increasing trend. A characteristic ‘bulging’ deformation pattern was observed, with peak horizontal displacements occurring at approximately two-thirds of the wall height. Furthermore, vertical earth pressure exhibited a clear diffusion pattern, attenuating downward from the loading plate. The computed potential failure surface aligns closely with the 0.3H surface (where H is the wall height) specified in current design codes, providing a robust theoretical basis for the seismic and dynamic design of railway retaining structures.
Acetamiprid (ACE) is a widely used neonicotinoid insecticide with high insecticidal efficacy; however, its residues in food and environmental matrices have raised concerns regarding potential risks to human health. In this work, a DNA walker amplification strategy integrating the dual electrochemiluminescence (ECL) quenching pathways of ZIF-67-derived hollow CoFe Prussian blue analogue nanozyme (denoted ZIF-67@CoFe PBA NZ) was proposed for sensitive detection of ACE. Through efficient self-assembly of luminol, Eu3+, and guanosine 5'-monophosphate disodium salt (GMP), the obtained luminol-Eu3+-GMP coordination polymer (Lu-Eu3+-GMP CP) exhibited aggregation-induced electrochemiluminescence (AIECL) characteristics and a stronger and more stable ECL signal. ZIF-67@CoFe PBA NZ exerted a favorable ECL quenching effect and achieved a quenching efficiency of 68.16% through reactive oxygen species (ROS) depletion and ECL resonance energy transfer (ECL-RET). Leveraging the above advantages and DNA walker-mediated signal amplification, the proposed ECL aptasensing platform enabled ACE detection, showing a broad linear range from 1.0 pg/mL to 100 ng/mL and a low detection limit of 0.43 pg/mL. This ECL aptasensing strategy exhibited excellent practical applicability and held great application prospects for food safety analysis.
As a blood biomarker associated with cerebral infarction (CI), the ultrasensitive detection of S100 calcium-binding protein B (S100B) is of great significance for the early warning of CI. Electrochemiluminescence (ECL) technology holds tremendous application potential due to its high sensitivity and low background noise. However, the further expansion of ECL applications is often limited by low efficiency. In particular, gold nanoclusters (NCs) typically undergo significant nonradiative decay due to the vibrational and rotational motion of their ligands. Regulating the metal-organic frameworks structure and synergistically enhancing it with coreactant accelerators is an effective strategy to overcome this performance bottleneck. In this study, we constructed an ECL system with dual enhancement effects of emitter and coreactant sides. At the emitter side, bovine serum albumin (BSA)-stabilized AuNCs (BSA-AuNCs) were loaded onto pleated Ce-MOF (B-AuNCs/Ce-MOF), and nonradiative decay was suppressed through the rigidification effect, resulting in 1.73 times the ECL efficiency of BSA-AuNCs. At the coreactant side, NiFe-PBA nanomaterials (Ni/Fe precursor molar ratio of 3:2) were engineered to serve as coreactant accelerators. Density functional theory (DFT) calculations indicated that the model constructed with a Ni/Fe precursor ratio of 3:2 exhibited the most favorable adsorption energy of TEA, with an adsorption energy of -0.432 eV. Consequently, the B-AuNCs/Ce-MOF+NiFe-PBA system exhibited 2.12 times the ECL efficiency of BSA-AuNCs. Based on this synergistically enhanced system, ultrasensitive detection of the CI biomarker S100B was achieved, with a linear range of 0.1 pg/mL-100 ng/mL and a detection limit of 0.03 pg/mL (S/N = 3). The method also demonstrated excellent stability, reproducibility and selectivity. This strategy provides a new approach for the early diagnosis and precise detection of acute CI.
We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.
