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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Jing-Chao Wang

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Review Open access Aug 2026

URMylation Signaling Pathway in Cancer: Molecular Mechanisms and Therapeutic Opportunities

Ubiquitin-related modifier 1 (URM1) defines a distinctive ubiquitin-like system in which URM1 functions both as a covalent protein modifier and a sulfur carrier required for wobble uridine (U34) thiolation of cytosolic tRNAs. This dual role places URM1 signaling at the intersection of protein post-translational modific...

Jing-Chao Wang, Pei-Qiang Yan, Wei-Wei Jiang et al. · 0 citations
Open access Sep 2026

MAPK signaling links BRD2 chromatin occupancy to PI3K/AKT inhibitor sensitivity

Bromodomain and extra-terminal (BET) proteins, BRD2, BRD3, BRD4, and BRDT, couple histone acetylation to transcription by recruiting elongation and transcription factor complexes to chromatin. Although BET proteins are promising therapeutic targets, the functions of individual family members remain incompletely underst...

Josefina Mendez, Simone Bruno, Alexandra Indeglia et al. · 0 citations

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