Open access
Aug 2026
ASOCompass: Context- and Chemistry-Aware Activity Prediction for Transferable Antisense Oligonucleotide Screening
ASOCompass, a context-and chemistry-aware framework for ASO activity prediction and candidate ranking, is introduced and the potential of jointly modeling sequence, chemistry, and experimental-biological context for transferable ASO screening is demonstrated.
Shu-Yu Liu, Jin Zhuo, Shuchang Lei et al.
· bioRxiv · 0 citations