Author

Jin-Xin Miao

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Open access Sep 2026

A late-stage multi-dimensional intervention rescues lethal viral pneumonia in an aged hamster model

This study initiated a multidimensional combination therapy of dexamethasone, heparin and the broad-spectrum viral decoy CoVR-MV at three days after infection and resulted in a potent reduction of high mortality, body weight loss, viral load, lung pathology and cytokine storm.

Ming Zhou, Xuan Liu, Jin-Xin Miao et al. · Molecular Biomedicine · 0 citations

Aug 2026

Lineage-specific pulmonary transcriptome landscape of coronavirus infection unveils universal immunotherapy for viral pneumonia.

It is demonstrated that a rational combination of pharmacological targeting of innate and adaptive immune responses is sufficient to reduce mortality and severe illness caused by beta, delta and EG.1 variants in SARS-CoV-2 infection.

Ming Zhou, Xuan Liu, Haiqing Xiao et al. · Molecular Therapy · 0 citations