Open access
Aug 2026
Combinatorial metabolic engineering of Mycobacterium neoaurum LY-2 for efficient androstenedione production from phytosterols
Androstenedione (AD) is an important precursor for the synthesis of corticosteroids, sex hormones, and other high-value steroid pharmaceuticals. Microbial conversion of phytosterols provides a sustainable route for AD production, but current production levels remain insufficient for practical industrial application. In...
Liyang Xu, C. Peng, Wenjing Pan et al.
· Synthetic and Systems Biotec... · 0 citations