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Author

Jinsong Jiang

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2 papers indexed here

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Sep 2026

A novel mTORC1-NPC2 axis suppresses lipophagy and drives atherosclerotic plaque progression.

BACKGROUND Endothelial dysfunction is a critical initiating factor in atherosclerosis (AS), with NPC2 and mTORC1 playing key roles in the regulation of endothelial lipophagy. OBJECTIVE To reveal that hypercholesterolemia disrupts endothelial lipophagy via the mTORC1-NPC2 axis and to explore its role in atheroscleroti...

Le-Gao Chen, Wei-Qin Lu, Long Piao et al. · 0 citations
Review Open access Aug 2026

Pediatric dilated cardiomyopathy and the progression to heart failure: mechanisms and interventions focusing on the “gene-inflammation-metabolism” axis

A pediatric-specific triaxial framework is presented that unifies known DCM pathways into a single actionable model for precision risk stratification and targeted therapy, and supports the development of novel biomarkers, multi-dimensional risk stratification strategies, and targeted interventions.

Jin-Song Jiang, D. Luo, Yan Gu et al. · 0 citations

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