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Author

Jin Liu

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Aug 2026

The DreAM-plus integrative RNA switch enhances transient AAV expression and reduces side effects of gene editing.

DreAM-plus, a multilayer RNA switch that integrates an aptamer-based polyA regulator (pA), a drug-elicitable alternative splicing module (DreAM) and an engineered P2A element with conditional upstream open reading frames (uORFs), achieves transient expression of an array of gene editors with a temporal resolution less...

Yue-Yang Zhang, Yuhan Yang, Zhanzhao Liu et al. · 0 citations

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