Author

Jin-Li Han

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Review Open access Sep 2026

The neuro-immune axis in cancer: mechanisms of neural regulation of immunity within the tumor microenvironment to promote cancer progression

The tumor microenvironment (TME) is a complex and dynamic ecosystem composed of cancer cells, stromal cells, immune cells, and the extracellular matrix, which significantly influences the initiation, progression, and therapeutic response of cancer. Emerging evidence indicates a crucial interaction between the nervous a...

Zhi-Fan Ran, Cheng-Hong Zeng, Jin-Li Han et al. · Frontiers in Immunology · 0 citations

#protein folding Aug 2026

PRDX1 drives colorectal cancer progression and immune microenvironment remodeling by facilitating PRMT5 nuclear translocation to activate Wnt/β-catenin signaling.

Findings identify a novel PRDX1-PRMT5 axis that activates Wnt/β-catenin signaling, highlighting a potential therapeutic strategy for CRC by targeting this pathway to suppress tumor progression and remodel the immune microenvironment.

Nianhua Yu, Xi Li, Jin-Li Han et al. · International Journal of Bio... · 0 citations