Aug 2026
Structural insights into the ADP-bound p97/VCP ND1 hexamer revealed by room-temperature XFEL crystallography.
p97/VCP ATPase uses adenosine triphosphate (ATP) hydrolysis to remodel protein assemblies and unfold substrates across diverse cellular processes, including protein quality control, membrane fusion, and chromatin regulation. Although cryogenic structural studies have provided valuable snapshots of distinct nucleotide s...
Seri Koh, H. Jeon, Eunsoo Lee et al.
· International Journal of Bio... · 0 citations