Author

Jin-Hai Luo

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Open access Sep 2026

Dual Modulation of Lipid Metabolism by Adzuki Bean (Vigna angularis) Saponins Involving PPARα/γ Signaling and Gut Microbiota Remodeling in Obesogenic Diet-Induced Obese Mice

Obesity is a prevalent metabolic disorder characterized by excessive lipid accumulation. This study aimed to investigate the anti-obesity effects and underlying mechanisms of two triterpenoid saponin-rich extracts, designated disaccharide saponin-rich extract (DTS) and trisaccharide/tetrasaccharide saponin-rich extract...

Qing-Feng Guo, Jin-Hai Luo, Xia Zhang et al. · Foods · 0 citations

Open access Aug 2026

Nomilin Ameliorates Insulin Resistance via Modulating the Glucose Metabolism and PI3K/Akt/GLUT4 signaling pathway in Type 2 Diabetes

This study illustrated that nomilin alleviated insulin resistance via activation of PI3K/Akt/GLUT4 signaling pathways, alleviating ROS accumulation and damage, and AGEs production, and improving the mitochondrial function.

Jin-Can Luo, Jin-Hai Luo, Bin-Cheng Han et al. · Food Science and Human Welln... · 0 citations

Open access Jul 2026

Molecular mechanisms of phytochemicals from Zanthoxylum nitidum (Roxb.) DC. against hepatocellular carcinoma: insights from network pharmacology, molecular docking, and bioinformatics.

The multi-target anti-HCC mechanisms of Z. nitidum (Roxb.) DC are revealed, offering evidence for its clinical use and stable binding between plant components and core targets is confirmed.

Rongjie Zhang, Ge Zhou, Jin-Hai Luo et al. · Artificial Cells Nanomedicin... · 0 citations