Open access
Jul 2026
Drug Functional Site-Unknown Molecular Targets Exemplified by SARS-CoV-2 pseudoknot and ribosomal frameshifting-modulators
This framework establishes a generalizable strategy for rationally targeting structured RNAs with repurposed drugs and offers new opportunities to expand the druggable genome to include noncoding RNA elements and other biomolecular targets lacking known functional sites.
A. Ragab, C. L. Ortiz, Yu-Tong Huang et al.
· bioRxiv · 0 citations