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Author

Jin-Deng Liao

2 papers indexed here

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Open access Sep 2026

The marine drug plitidepsin alleviates osteoporosis in estrogen-deficient mice by suppressing ROS-mediated NRF2/HO-1 signaling and osteoclast formation

Marine-derived compounds represent an important source of innovative therapeutics owing to their structural diversity and broad bioactivity; however, their potential in osteoporosis therapy remains insufficiently explored. This study investigated the effects of plitidepsin (Pli), a marine-origin cyclic peptide, on os...

Jin-Deng Liao, Liang Liao, Qiu-Fei Li et al. · 0 citations
Sep 2026

Cyclovirobuxine Prevents Osteoclastogenesis and Estrogen Deficiency-Induced Bone Loss by Inhibiting ROS Generation via the PI3K/AKT/FOXO1 Pathway

The results suggest that CVB suppresses osteoclastogenesis and their resorptive function through modulation of MAPK and PI3K/AKT/FOXO1 pathways and by enhancing antioxidant defense, which has potential therapeutic value for antiosteoporosis treatment.

Qiu-Fei Li, Na Hai, Jin-Deng Liao et al. · 0 citations

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