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Review Open access Aug 2026

Prefrontal-limbic circuit modulation in anxiety disorders: Differential neural effects of psychotherapy versus pharmacotherapy revealed by ALE meta-analysis

Abstract Background Anxiety disorders (ADs) involve dysregulation of prefrontal–limbic circuits, but the neural effects of psychotherapy and pharmacotherapy remain unclear. Methods We conducted an activation likelihood estimation (ALE) meta-analysis of task-based fMRI studies reporting pre- and post-treatment whole-bra...

Juan Qiu, Junjie Ren, Jin Chang et al. · 0 citations

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