Jin-Bo Guo

Norcantharidin induces apoptosis in hepatocellular carcinoma MHCC97-H cells in association with altered NF-κB/IκBα signaling dynamics and JNK activation.

Norcantharidin (NCTD), a demethylated derivative of cantharidin, has antitumor activity against multiple cancer types; however, its effects on the NF-κB/JNK signaling axis in hepatocellular carcinoma (HCC) remain incompletely defined. MHCC97-H HCC cells were treated with NCTD at 5, 20, and 40 μg/mL (approximately 29.7,...