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Author

Jill M. Lawrence

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Open access Aug 2026

In vivo genome editing of central nervous system SIV reservoirs in ART-suppressed rhesus macaques

It is demonstrated that intact and potentially replication-competent virus persists in the primate brain under ART and that systemic AAV9-CRISPR can reach and edit proviral DNA in this sanctuary, supporting genome editing as a strategy toward durable remission of CNS reservoirs.

Hong Liu, Shu-Ren Liao, Chen Chen et al. · 1 citation

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