#protein folding
Aug 2026
Mechanistic Characterization of NABi as a Selective Inhibitor of SOD1G93A Aggregation: Structural Basis and Therapeutic Implications for ALS
These findings establish NABi as a promising therapeutic candidate for SOD1G93A-associated familial ALS, demonstrating its capacity to selectively target pathological protein conformations while preserving normal cellular function.
Min-Kyung Nam, Yeram Oh, Yemi Choi et al.
· ACS Chemical Neuroscience · 0 citations