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Review Sep 2026

Epigenetic Reprogramming in Cadmium-Associated Liver Injury: Evidence, Mechanistic Insights, and Therapeutic Perspectives.

Chronic cadmium (Cd) exposure is associated with adverse liver outcomes, including metabolic dysfunction-associated steatotic liver disease (MASLD), inflammation, and fibrosis, yet the mechanisms underlying persistent hepatic injury remain incompletely resolved. This review critically examines population-based and expe...

Xing Zhang, Na Liu, Jie Zhou · 0 citations
Open access Aug 2026

DACH1 SUMOylation protects against diabetic cardiomyopathy by suppressing endoplasmic reticulum stress.

INTRODUCTION Endoplasmic reticulum (ER) stress is a key driver of diabetic cardiomyopathy (DCM), but its upstream regulators are incompletely defined. The transcription factor DACH1 is genetically linked to diabetes and cardiovascular risk, yet its role in the diabetic heart is unknown. OBJECTIVES This study aimed to...

Jie Lin, Na Liu, Bo Li et al. · 0 citations

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