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Author

Jie Zheng

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Open access Oct 2026

Plasma Angiotensin-Converting Enzyme as a Prioritized Candidate Target for Alzheimer's Disease: Evidence From Proteome-Wide Mendelian Randomization and a Large Prospective Cohort Study.

Genetic analyses prioritized angiotensin-converting enzyme as a candidate target, and a conventional observational analysis in a large prospective cohort provided supportive evidence that regular angiotensin-converting enzyme inhibitor use was associated with a higher AD risk.

Pei-Guan Huang, Hai-Bo Tang, Ze-Ying Feng et al. · 0 citations
Open access Aug 2026

Elucidating the proteomic pathways linking childhood body mass index with type 2 diabetes: a Mendelian randomization and recall-by-genotype study

The authors' study identified putative actionable proteins that could reduce the elevated T2D risk attributable to childhood adiposity in Europeans, but their relevance in Asian populations requires further investigation.

Siyu Chen, Yiwen Liang, Shan Luo et al. · 0 citations

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