Author

Jie-Yu Li

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Open access Jul 2026

Activation of the NF-κB/ALDH1A1 signaling promotes non-mutational resistance to EGFR-TKIs in non-small cell lung cancer

The NF-κB/ALDH1A1 signaling is established as a key non-genetic mechanism of acquired EGFR-TKI resistance and a rational combination strategy to overcome it is provided.

Ling-Yu Zhang, Gui-Bin Weng, Chunjiang Liu et al. · Oncogene · 0 citations

Open access Jul 2026

A Rho GTPase-related gene signature predicts prognosis and reveals an immunosuppressive microenvironment in lung adenocarcinoma: an integrated analysis of bulk and single-cell RNA sequencing data

A robust prognostic model based on four RhoGTPase-related prognostic genes was established, effectively stratifying LUAD patients and provides valuable insights into the heterogeneity of LUAD and has the potential to inform personalized therapeutic strategies.

Tian-Chuan Li, Dan-Hong Wu, A. Yang et al. · Scientific Reports · 0 citations