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Review Open access Sep 2026

Hepatobiliary phase imaging in HCC: revisiting diagnostic algorithms and clinical utility of gadoxetic acid-enhanced MRI across international guidelines

Hepatocellular carcinoma (HCC) remains a major cause of cancer-related mortality worldwide. In at-risk populations, noninvasive imaging diagnosis relies primarily on the vascular hallmarks of arterial phase hyperenhancement and washout appearance. However, these features are often absent in early hepatocarcinogenesis,...

Shu-Wei Zhou, Jie Yang, Shu-Hang Zhang et al. · 0 citations
Open access Sep 2026

SHP2 induced 125I radiotherapy-resistant in cervical cancer via modulating ERK/E2F1/SKP2 and P53/AMPK/FOXO signaling induced apoptosis and proliferation

To elucidate the molecular mechanismthrough which SHP2 confers resistance to 125I radiotherapy in cervical cancer by promoting the ERK/E2F1/SKP2 pathway while antagonizing the P53/AMPK/FOXO pathway. Bioinformatics analysis was employed to identify SHP2 associated genes.In vivo experiments assessed tumor progression v...

Hai-Ping Song, Jie Yang, Rong-Na Liu et al. · 0 citations

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