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Review Open access Sep 2026

Immunotherapy of membranous nephropathy: strategic evolution from CD20 monoclonal antibodies to future vaccines

Membranous nephropathy (MN) arises from autoantibody-mediated attack on podocyte antigens, with immune deposits forming subepithelially at the glomerular basement membrane to trigger complement activation and subsequent podocyte damage, eventually manifesting as proteinuria. Traditional therapy hinges on nonspecific im...

Ke-Na Yu, Xi-Fang Xu, Jun-Wei Gao et al. · 0 citations
Review Sep 2026

The Role of Natural Products in Ameliorating Mitochondrial Dysfunction in Diabetic Kidney Disease and the Underlying Mechanisms.

Diabetic Kidney Disease (DKD), a prevalent microvascular complication of diabetes mellitus, represents the leading cause of end-stage renal disease worldwide. Its pathogenesis is multifactorial, involving metabolic disturbances, oxidative stress, inflammatory responses, and notably, mitochondrial dysfunction. Mitochond...

Yun-Zhou Wu, Jun-Wei Gao, Jia-Zhe Lin et al. · 0 citations

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