Jie Ren

A ROS-Responsive Coordination Nanoplatform Integrates Antibacterial Activity with STING-Activating Immunomodulation to Attenuate Periodontitis.

Antibacterial treatment reduces residual bacterial burden in periodontitis, but rapid bacterial killing and lysis can also increase exposure to danger signals such as bacterial DNA (bDNA), which can contribute to cGAS-STING-associated innate immune activation. To address this bactericidal stress-associated inflammation...