Jie-Mei Zhuang

High-Gain Bacterial RNA Imaging via High-Density Protein Fluorescence In Situ Hybridization

Fluorescence in situ hybridization (FISH) is important for bacterial genotypic analysis; however, the limited number of labels per probe results in insufficient signal gain, compromising the detection of low-abundance RNAs. Here, we present high-density protein FISH (HD-FISH) for high-gain bacterial RNA imaging. Inst...