Author

Jie-Jun Xu

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Preprint Oct 2026

REST: Reliability-Guided Spatial Transcriptomics Supervision for Gene Expression Prediction from Histopathological HE-Stained Images

Histopathology is central to cancer diagnosis, but morphology in Hematoxylin and Eosin (HE)-stained images does not directly reveal the molecular states that characterize disease heterogeneity and inform tumor characterization, prognostic assessment, and biomarker discovery. Spatial Transcriptomics (ST) measures spatia...

Lan-Feng Zhong, Xiang-Yu Sun, Gui-Xuan Xu et al. · 0 citations

Open access Sep 2026

Genome-Wide Characterization of the Cinnamyl Alcohol Dehydrogenase (CAD) Gene Family and Expression Profiling of Candidate ClCAD3 Gene Associated with Lignin Biosynthesis in Watermelon

Cinnamyl alcohol dehydrogenase (CAD) catalyzes the final step in lignin monomer biosynthesis and is crucial for plant cell-wall lignification. However, the CAD gene family and its role in watermelon rind lignification are poorly understood. In this study, we performed genome-wide bioinformatics analysis to identify the...

Tian-Tian Yang, Li-Yuan Yang, Jie-Jun Xu et al. · Horticulturae · 0 citations