Author

Jie Guo

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Open access Oct 2026

Adverse Event Reporting Patterns Associated with Concomitant Use of 5-HT3 and NK-1 Receptor Antagonists: A Large-Scale Spontaneous-Reporting Analysis

Background/Objectives: Chemotherapy-induced nausea and vomiting (CINV) is common and compromises quality of life and adherence. 5-HT3 receptor antagonists (RAs) and NK-1 RAs are cornerstones, yet adverse event patterns associated with their concomitant use are not well characterized. Methods: We queried the US Food and...

Rui-Qi Zhao, Shi-Qi Tang, Meng-Yao Han et al. · Pharmaceuticals · 0 citations

Open access Sep 2026

Deciphering the Genetic Underpinnings of Liver Cirrhosis–Heart Failure Comorbidity Through Multi-Omics: CRIM1 as a Key Endothelial Mediator

An integrative multi-omics pipeline encompassing GWAS meta-analysis, gsMap-based spatial transcriptomic projection, GeneEnrich functional annotation, single-cell atlas construction, seismicGWAS and ECLIPSER cell-type scoring, eCAVIAR and fastenloc colocalization, hdWGCNA network inference, scTenifoldKnk in silico gene...

Rui-Qi Zhao, Jie Guo, Meng-Yao Han et al. · International Journal of Mol... · 0 citations