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Review Open access Sep 2026

Functionalized GelMA-based hydrogels for osteoimmunomodulation and bone regeneration

Complex bone defects caused by trauma, infection, tumor-related bone loss and metabolic disorders remain clinically challenging because an inflammatory imbalance, impaired vascularization and insufficient osteogenesis often coexist. Gelatin methacryloyl (GelMA) hydrogels are attractive matrices for bone regeneration ow...

Li Chen, Jing-Yao Tan, Mao-Lin Li et al. · 0 citations
Open access Sep 2026

An Injectable and Photocrosslinkable Hydrogel Based on Recombinant Human Collagen Type XVII Promotes Osteochondral Regeneration by Activating the TGF β/SMAD Signaling Pathway

This study establishes the pivotal role of collagen type XVII in cartilage regeneration, presenting a promising, minimally invasive strategy with mechanical adaptability and active inductive functionality for functional cartilage defect repair, and expands the cross-tissue application prospects of rhCOL17.

Guan-Ying Yang, Wei Li, Yan-En Wang et al. · 0 citations

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