KLF14 inhibits EMT in esophageal cancer cells through inhibition of the MISP-Wnt/β-catenin signaling axis.
BACKGROUND AND OBJECTIVES Esophageal squamous cell carcinoma (ESCC) dominates esophageal malignancies, and metastasis largely accounts for its dismal prognosis. Epithelial-mesenchymal transition (EMT) is a core driver of tumor metastasis. Mitotic spindle positioning protein (MISP) correlates strongly with EMT, yet its...