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Jiaying He

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Jul 2026

ABOPD: Antibody CDR Design via On-Policy Distillation

ABOPD is introduced, an antibody design framework based on on-policy distillation that leverages privileged native geometry during training to supervise states visited along the model's own denoising trajectories, offering a path to higher-fidelity protein design.

Zhuo Yang, Jiaying He, Jiaqing Xie et al. · 0 citations
Preprint Jul 2026

Rethinking Scientific Discovery in the Agentic Era

Applications in materials analysis, molecule design, and protein or antibody screening, together with experiments on scientific reading, idea generation, molecule generation, and antibody screening, show that SCION outperforms existing autonomous research-agent baselines, especially in decomposition, verification, refi...

Y. Zheng, Yuxin Wang, Jiahao Lu et al. · 0 citations

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