Zwitterionic Polarization‐Engineering Covalent Organic Frameworks for Targeted Ferroptosis‐Synergistic Photothermal Immunotherapy
This study constructed two isomorphic frameworks featuring distinct electronic topologies: a zwitterionic squaric acid (SA) COF with inherent electrostatic asymmetry, and a charge‐neutral terephthaldehyde (TA) COF, which eliminates primary tumors, produces abscopal effects, and establishes immune memory against recurre...