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Jiaqiang Wang

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Open access Aug 2026

TUG1 supports mouse two-cell-stage development and ZGA-associated transcription through MAPK8 signaling

It is demonstrated that TUG1, which is highly expressed in tumors, regulates early embryonic development in mice and is transformed from a cancer-specific effector to a critical regulator of the ZGA, raising the possibility that related regulatory principles may operate in other biological contexts.

Jian-Wu Wang, Guang Yang, Qingbo Yang et al. · 0 citations

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