Mutations in dfrA and its upstream region are associated with para-aminosalicylic acid resistance in Mycobacterium tuberculosis
It is demonstrated that mutations in dfrA coding and upstream regulatory regions contribute to para-aminosalicylic acid resistance in Mtb clinical isolates by integrating genomic analysis with functional assays of thermal stability, promoter activity and drug susceptibility.
Rong Zeng, Najeeb Ullah, Jing Gu et al.
· JAC-Antimicrobial Resistance · 0 citations