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Author

Jianwei Sun

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Sep 2026

Exon 21 skipping in ARHGAP10: A splicing switch that governs breast cancer metastasis.

Rho GTPase-activating protein 10 (ARHGAP10) is recognized as a tumor suppressor, yet the functional impact of its alternative splicing isoforms on breast cancer metastasis remains unclear. This study aimed to elucidate the role and regulatory mechanism of ARHGAP10 exon 21 skipping in breast cancer progression. Our rese...

Zhi-Wei Wu, Meng-Zhen Huang, Liu Yu et al. · 0 citations
Review Open access Jul 2026

Cancer stem cells and drug resistance in cancer: molecular mechanisms and therapeutic targets

A comprehensive synthesis of the molecular and microenvironmental mechanisms underlying CSC-driven drug resistance is provided and emerging therapeutic strategies targeting CSC plasticity, niche interactions, metabolic adaptation, and immune evasion are critically discussed.

Hayam Hamdy, Youzhou Li, Chen Li et al. · 0 citations

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