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Author

Jiansen Cao

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Open access Jul 2026

Lgals3high Macrophages Orchestrate Neuroinflammation and Extracellular Matrix Remodelling via NF-κB Pathway in Acute Spinal Cord Injury.

Lgals3high macrophages are core drivers of ECM remodelling in ASCI via a Lgals3/NF-κB/p65/Ccl2 signalling axis that couples M1 polarization with monocyte recruitment and exerts therapeutic effects by regulating macrophage polarization and ECM remodelling, providing a novel "immune-matrix" dual-targeting strategy.

Yaping Feng, Ling Yang, Yuyang Liu et al. · 0 citations

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