Metallaphotocatalytic Assembly of Unsymmetrical 1,4-Diketones via Dual Acyl Units: Divergent Initiation of Carboxylic Acids and Aldehydes
1,4-Diketones, classic umpolung motifs, have long posed a grand challenge for their efficient synthesis in organic and pharmaceutical synthesis. Herein, we report a nickel/photoredox dual-catalyzed three-component coupling of carboxylic acids, aldehydes, and alkenes. This strategy enables the discriminative introduct...