Author

Jianguo Yang

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Open access Jul 2026

A decoupled transcription platform enables tunable and predictable gene expression in yeast

CRISPR-Activated Promoter-based Orthogonal expression (CAPO) is developed, a CRISPR-guided system that tunes gene activity in yeast and enables multiplex colour generation and faster optimization of metabolic pathways.

Yu-Jie Chen, Hui Li, Lingling Duan et al. · Nature Communications · 0 citations