Author

Jiangang Hu

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Jul 2026

A xanthone derivative MGS-3, confers protection against Staphylococcus aureus infection through SarA-mediated inhibition of alpha-hemolysin expression.

Results establish SarA suppression as MGS-3's primary anti-virulence mechanism, and MGS-3 represents a promising candidate for anti-staphylococcal drug development, targeting virulence rather than bacterial viability to potentially curb resistance evolution.

Han Bai, Yuehan Zhou, Wen-Chong Ye et al. · Microbial Pathogenesis · 0 citations

Open access Aug 2026

The (p)ppGpp Synthetase RelA Contributes to Virulence, Competition Capability and Antibiotic Resistance of Avian Pathogenic Escherichia coli

It is indicated that relA plays a key role in APEC virulence, antibiotic resistance, and membrane homeostasis, and could provide a theoretical basis for targeting the stringent response as a potential strategy to control avian colibacillosis.

Jiangang Hu, Dossêh Jean Apôtre Afayibo, Chang Liu et al. · Microorganisms · 0 citations

Open access Jul 2026

H-PBFT: A Hierarchical and Credit-Aware PBFT Consensus Mechanism for Blockchain-Based Intelligent Transportation Systems

Simulation results show that compared with standard PBFT, Q-PBFT, and APBFT, H-PBFT exhibits significant advantages in consensus latency, throughput, and view switching recovery time, and maintains high system robustness even in complex network environments with malicious nodes.

Zhen-Hua Wang, Jiangang Hu, Xinmeng Wang et al. · Future Internet · 0 citations