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Author

Jiang-Wei Wu

2 papers indexed here

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Open access Oct 2026

ZBED6 deficiency drives pathological cardiac hypertrophy through MEOX1–ERK1/2–dependent autophagy dysfunction

Pathological cardiac hypertrophy, a major risk factor for heart failure, is regulated by complex transcriptional networks. We previously identified the transcription factor ZBED6 as a key regulator for skeletal muscle hypertrophy, its role in the cardiac hypertrophy remains unexplored. Here, we report that ZBED6 is a k...

Xiao Zhang, Xiao-Peng Liu, Rui-Rui Pan et al. · 0 citations
Open access Oct 2026

ZBED6 deletion activates FNDC1-mediated PI3K/AKT and MAPK/ERK1/2 signaling pathways to promote myogenesis in pigs

FNDC1, a muscle-derived secreted factor, is identified as a previously unrecognized direct transcriptional target of ZBED6, supporting the ZBED6-FNDC1 axis as a regulatory mechanism contributing to porcine myoblast proliferation and differentiation.

Xiao Zhang, Rui-Rui Pan, Miao-Miao Qin et al. · 0 citations

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