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Jiang-Bo Guo

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Open access Oct 2026

A “Progenitor Cell Ark” hydrogel system for intervertebral disc regeneration via mitochondrial targeting and mitophagy enhancement

Intervertebral disc degeneration (IVDD), driven by progenitor cell loss and oxidative stress, remains a major clinical challenge with limited effective regenerative therapies. Here, we present a “Progenitor Cell Ark,” a triple-layered hydrogel microsphere system designed for synergistic cell delivery and microenvironme...

Yi-Lin Yang, Yi-Xue Huang, Hao Liu et al. · 0 citations

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