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Jianfeng Chen

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Open access Aug 2026

Integrin α4β1 signaling modulates cell spreading and migration by dynamic regulation of paxillin expression

Leukocyte adhesion and migration are fundamental processes in immune responses, relying on the precise spatiotemporal regulation of integrin-mediated signaling. Although paxillin is known to function as a crucial adaptor protein in adhesion complexes, how its expression is regulated during dynamic cell motility remai...

Kang-Jing Ma, Ye Yuan, Jia-Hui Wang et al. · 0 citations

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