Author

Jian Zhang

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Open access Oct 2026

Large language models reveal a systematic preference in clinical immunotherapy guidelines: a multi-model comparative analysis

Clinical guidelines may sometimes contain divergent treatment recommendations, creating uncertainty in therapeutic decision-making. To evaluate the performance of four large language models (LLMs) (GPT-4o, Claude 3.7 Sonnet, Gemini 1.5 Pro, Deepseek-V3) in analyzing discrepancies between the American Society of Clini...

Zhen-Yu Chen, An-Qi Lin, Jun-Yi Shen et al. · Scientific Reports · 0 citations

Open access Aug 2026

Multicohort Construction, Immune Landscape Analysis, and PCOLCE2 Functional Validation of an Inflammation-Related Prognostic Model in Colorectal Cancer.

Colorectal cancer (CRC) prognosis remains challenging due to tumor heterogeneity and immune evasion driven by aberrant inflammatory signaling, and robust multicohort validated prognostic tools with clear therapeutic implications are still lacking. To address this gap, we integrated five independent CRC cohorts (TCGA, G...

Min-Jun Dong, Wen-Tao Xu, Jian Zhang et al. · Biofactors · 0 citations