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Author

Jian-Yu Wang

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Sep 2026

Gut microbiota-mediated dietary lignans metabolism drives accumulation of N,N-dimethylsphingosine and sensitizes triple-negative breast cancer to paclitaxel.

Results indicate that DL potentiate PTX efficacy in TNBC, at least in part, through microbiota-dependent accumulation of DMS, offering a rationale for microbiota-informed strategies to optimize chemotherapy in TNBC.

Jian-Yu Wang, Liu-Ying Zhao, Shi-Lu Zhao et al. · 0 citations

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